| President | Paul Locatelli, S.J. |
| Executive Assistant to the President | James Briggs |
| Assistant to the President | Simone J. Billings |
| General Counsel | John Ottoboni |
Provost and Vice President for Academic Affairs | Lucia Albino Gilbert |
| Senior Vice Provost | Don Dodson |
| Interim Vice Provost, Enrollment Management | Terry Shoup |
Vice Provost, Student Life, and Dean of Students | Jeanne Rosenberger |
| Vice Provost, Planning and Administration | Charles Erekson |
| Vice Provost, Information Services, and Chief Information Officer | Ron Danielson |
| Associate Vice Provost, Enrollment Management / Dean, University Financial Aid Services | Richard Toomey |
| Associate Vice Provost for Enrollment Management / Dean, Undergraduate Admission | Sandra Hayes |
| Vice President, Administration & Finance | Robert Warren |
| Associate Vice President, Finance | Harry Fong |
| Assistant Vice President, Human Resources | Molly McDonald |
| Vice President, University Relations | James Purcell |
| Assistant Vice President, Development | Nancy Trish Calderon |
| Executive Director, Alumni Relations | Kathryn Kale |
| Associate Vice President, Marketing and Communications | Richard Giacchetti |
| Dean, College of Arts and Sciences | W. Atom Yee |
| Interim Dean, School of Education, Counseling Psychology, and Pastoral Ministries | Dale Larson |
| Dean, Leavey School of Business | Barry Posner |
| Dean, School of Engineering | Godfrey Mungal |
| Dean, School of Law | Donald Polden |
| Chief Investment Officer | John Kerrigan |
| University Registrar | Monica Augustin |
| University Librarian | Elizabeth Salzer |
| Athletic Director | Daniel Coonan |
| Executive Director, Markkula Center for Applied Ethics | Kirk O. Hanson |
| Executive Director, Center for Science, Technology, and Society | Geoffrey Bowker |
| Executive Director, Ignatian Center for Jesuit Education | Kevin Quinn, S.J. |
| Director, Drahmann Advising and Learning Resources Center | Nedra Shunk |
| Director, Campus Ministry | John R. Treacy, S.J. |