Santa Clara University

Phone: 408 551-1898
Fax: 408 554-2710

Craig Stephens

Professor, Biology Department and Public Health Program

Educational Background

B.S. 1985 Roanoke College

Ph.D 1991 University of Virginia

Postdoctoral work (1991 - 1996) in the laboratory of Dr. Lucy Shapiro, Developmental Biology, Beckman Center, Stanford University

Teaching - Recent Courses since 2009

Biol 113 General Microbiology

Bio 135 Biofuels: Sustainable Energy for the Future

Bio 176 Recombinant DNA Technology

PHSC 1 Human Health and Disease

PHSC 120 Technology, Innovation, and Public Health
Research Papers

C. Stephens, B. Christen, K. Watanabe, T. Fuchs, and U. Jenal. (2007) Regulation of D-xylose metabolism in Caulobacter crescentus by a LacI-type repressor. Journal of Bacteriology 189: 8828-8834.

C. Stephens, B. Christen, T. Fuchs, V. Sundaram, K. Watanabe, and U. Jenal. (2007) Genetic analysis of a novel pathway for D-xylose metabolism in Caulobacter crescentus. J. Bacteriology 189:2181-2185.

S. Crosson, P. McGrath, C. Stephens, H. McAdams, L. Shapiro (2005).Conserved modular design of an oxygen sensory/signaling network with species-specific output. Proc Natl Acad Sci USA. 102: 8018-23.

A. Hottes, M. Meewan, D. Yang, N. Arana, P. Romero, H. McAdams, and C. Stephens (2003). Transcriptional profiling of Caulobacter crescentus during growth on complex and minimal media. J. Bacteriology 186: 1448-1461.

L. West, D. Yang, and C. Stephens (2002). Use of the Caulobacter crescentus genome sequence to develop a method for systematic genetic mapping. J. Bacteriology 184: 2155-2166.

Nierman et al.(including C. Stephens)(2001). Complete genome sequence of Caulobacter crescentus. Proc. Natl. Acad. Sci. 98: 4136-4141.

A. Berdis, I. Lee, J. Coward, C. Stephens, R. Wright, L. Shapiro, and S. Benkovic (1998). A cell-cycle regulated adenine DNA methyltransferase from Caulobacter crescentus processively methylates GANTC sites on hemimethylated DNA. Proc. Natl. Acad. Sci. (USA) 95: 2874-2879.

C. Stephens, C. Mohr, C. Boyd, J. Maddock, J. Gober, L. Shapiro (1997). Identification of the fliI and fliJ components of the Caulobacter Type III protein secretion system. Journal of Bacteriology. 17: 5355-5365.

R. Wright, C. Stephens, and L. Shapiro (1997). The CcrM DNA methyltransferase is widespread in alpha subdivision bacterial and its essential functions are conserved in Rhizobium meliloti and Caulobacter crescentus. Journal of Bacteriology 179: 5869-5877.

R. Wright, C. Stephens, G. Zweiger, L. Shapiro, and M. Alley (1996). Caulobacter Lon protease has a critical role in cell-cycle control of DNA methylation. Genes and Development. 10: 1532-1542.

C. Stephens, A. Reisenauer, R. Wright, and L. Shapiro (1996). A cell-cycle regulated bacterial DNA methyltransferase is essential for viability. Proc. Natl. Acad. Sci. (USA) 93: 1210-1214.

C. Stephens, G. Zweiger, and L. Shapiro (1995). Coordinate cell cycle control of a Caulobacter DNA methyltransferase and the flagellar genetic hierarchy. Journal of Bacteriology 177: 1662-1669.

C. Stephens and L. Shapiro (1993). An unusual promoter controls cell-cycle regulation and dependence on DNA replication of the Caulobacter early flagellar operon fliLM. Molecular Microbiology 9: 1169-1179.

R. Kadner, G. Murphy, and C. Stephens (1992). Two mechanisms for growth inhibition by elevated transport of sugar phosphates in Escherichia coli. Journal of General Microbiology 138: 2007-2012.

C. Stephens and R. Bauerle (1992). Essential cysteines in 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Escherichia coli : Analysis by chemical modification and site-directed mutagenesis of the phenylalanine-sensitive isozyme. Journal of Biological Chemistry 267: 5762-5770.

C. Stephens and R. Bauerle (1991). Analysis of the metal requirement of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Escherichia coli. Journal of Biological Chemistry 266: 20810-20819.

Invited Articles
J. Chen and C. Stephens (2007). Completing the circuit. Current Biology 17:R203-206.

C. Stephens (2006). Managing magnetosomes. Current Biology 16:R363-5.

C. Stephens (2005). Even bacteria get old. Current Biology (in press).

C. Stephens (2004). A new player on the cell cycle circuit. Current Biology 14: R505-507.

C. Stephens (2003). Tropical treasure. Current Biology 14: R65-66.

C. Stephens and M. Laub (2003). All that you can't leave behind. Current Biology 13: R571-573.

U. Jenal and C. Stephens (2002). The Caulobacter cell cycle - Timing, spatial regulation, and checkpoints. Current Opinion in Microbiology.

C. Stephens (2002). Pushing plasmids apart. Current Biology.

C. Stephens (2002). Breaking down biofilms. Current Biology 12: 132-134.

C. Stephens (2001). Seeing the big picture with microarrays. Current Biology 11: 222-225.

C. Stephens and W. Murray (2001). Pathogen evolution: How good bacteria go bad. Current Biology 11: 53-56.

C. Stephens (2000). Intimate strangers. Current Biology 10: 272-275

C. Stephens (1999). The migrating kinase and the master regulator. Current Biology 9: 493-496.

C. Stephens (1998). Getting folded proteins across membranes. Current Biology 8: 578-581.

C. Stephens (1997). Bacterial sporulation : A question of commitment. Current Biology 8: 45-48.

C. Stephens and L. Shapiro (1997). Bacterial protein secretion : A target for new antibiotics. Chemistry and Biology 4: 637-641.

C. Stephens and L. Shapiro (1996). Delivering the payload. Current Biology 6: 927-930.

U. Jenal and C. Stephens (1996). Sizing up sporulation. Current Biology 6: 111-114.

U. Jenal, C. Stephens, and L. Shapiro (1995). Regulation of asymmetry and polarity during the Caulobacter cell cycle. Advances in Enzymology 71: 1-40.

C. Stephens, U. Jenal, and L. Shapiro (1995). Expression of polarity during Caulobacter differentiation. Seminars in Developmental Biology 6: 3-13.

C. Stephens, M. Singer, and L. Shapiro (1994). An ATP/ADP switch. Current Biology 4: 630-634.