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Publications

Selected Publications

  • Droplet microfluidic platform for the determination of single-cell lactate release, Analytical Chemistry, 88, 3257-3263 (2016).
  • Three-dimensional matrix stiffness and adhesive ligands affect cancer cell response to toxins, Biotechnology and Bioengineering, 113, 443-452 (2016).
  • Experimental Investigation of mechanical and thermal properties of silica nanoparticle-reinforced poly(acrylamide) nanocomposite hydrogels. PLoS One, 10, e0136293 (2015).
  • A novel 2.5D culture platform to investigate the role of stiffness gradients on adhesion-independent cell migration, PLoS One, 9, e110453 (2014).
  • Role of three-dimensional matrix stiffness in regulating the response of human neural cells to toxins, Cellular and Molecular Bioengineering, 7, 278-284 (2014).
  • Function, structure, and stability of enzymes confined in agarose gels, PLoS One, 9, e86785 (2014).
  • Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells, Integrative Biology, 4, 1049-1058 (2012).
  • Directed evolution of adeno-associated virus for enhanced gene delivery and gene targeting in human pluripotent stem cells, Molecular Therapy, 20, 329-338 (2012).
  • An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells, Molecular Therapy, 19, 667-675 (2011).
  • Polymer-nanotube-enzyme composites as active antifoulding films, Small, 3, 50-53 (2007).
  • Protein directed formation of silver nanoparticles on carbon nanotubes, Advanced Materials, 19, 3167-3170 (2007).
  • Nanotube-enzyme conjugates in room temperature ionic liquids, Applied Biochemistry and Biotechnology, 143, 153-164 (2007).
  • Directed assembly of carbon nanotubes at liquid-liquid interfaces, Journal of the American Chemical Society, 128, 1046-1047 (2006).
  • Increasing protein stability through control of the nanoscale environment, Langmuir, 22, 5833-5836 (2006).

Reviews, Books, and Book Chapters

  • Advances in homology directed genetic engineering of human pluripotent stem cells (Invited Review), World Journal of Stem Cells, 5, 98-105 (2013).
  • Developments in Biotechnology and Bioprocessing, American Chemical Society Symposium Series, Volume 1125 (2013).
  • Delivery of therapeutics using carbon nanomaterials (Invited Book Chapter), Applications of Nanomaterials, American Scientific Publishers (2013).
  • Biomolecule-nanomaterial interactions: Effect on biomolecule structure, function, and stability, Biological Interactions on Nanomaterial Surfaces, Springer, 97-114 (2009).
  • Preparation and characterization of carbon nanotube-protein conjugates, Methods in Bioengineering, Artech House, 1-23 (2009).
  • Protein-carbon nanotube conjugates, ACS Symposium Series, 986, 100-115 (2008).
  • The protein-nanomaterial interface, Current Opinion in Biotechnology, 17, 562-568 (2006).

Selected Conference Presentations

  • Investigating cancer cell migration guided by stiffness gradients, AIChE Annual Meeting, San Francisco, CA, November 2016. 
  • Studying the effects of functionalized multi-wall carbon nanotubes on mechanical and thermal properties of epoxy composites, Materials Science and Engineering Conference, Orlando, FL, September 2015.
  • Bioengineering design and innovation: Teaching an entrepreneurial mindset to undergraduate bioengineers, KEEN Winter Conference, Tempe, AZ, January 2015.
  • Role of 3D matrix stiffness and cell-matrix interactions in regulating the response of human cancer cells to cytotoxic compounds, AIChE Annual Meeting, Atlanta, GA, November 2014.
  • Elucidating mechanisms behind cell migration at polystyrene-hydrogel interfaces, CMBE Conference, La Jolla, CA, January 2014.
  • Fundamentals and applications of nanomaterial-biomolecule interactions, AIChE Annual Meeting, San Francisco, CA, November 2013. (Invited talk)
  • Investigating the relationships between mechanical and thermal properties of hydrogel nanocomposites, MRS Spring Meeting, San Francisco, CA, April 2013.
  • AAV-mediated gene delivery and gene targeting in human embryonic stem cells, ASGCT Annual Meeting, Seattle, WA, May 2011.
  • Microarray biochips for high-throughput metabolic toxicity assessment of drugs, ACS National Meeting, Washington, DC, August 2009.
  • Miniaturized three-dimensional cell culture and metabolic enzyme arrays for high-throughput toxicity assays, Forinvitox Forum Event, Sweden, May 2009.
  • Structure, function, and stability of enzymes covalently attached to oxidized carbon nanotubes, AICHE Annual Meeting, Philadelphia, PA, November 2008.
  • Enzyme-nanomaterial conjugates: Opportunities for functionally organized materials, 12th Mexican Biotechnology and Bioengineering Meeting, Mexico, June 2007.
  • Biologically-enabled and inspired design of hierarchically-organized functional and responsive materials, ACS National Meeting, Washington, D.C., August 2005.