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Publications

    1. Zhang, Z., Murphy, A., Hu, J., Kodadek, T. Genetic selection of short peptides that support protein oligomerization in vivo. Curr. Biol., 1999, 9, 417- 420.
    2. Zhang, Z., Zhu, W., Kodadek, T. Selection and application of peptide-binding peptides. NatureBiotechnol., 2000,18, 71-74.
    3. Zhang, Z., Ly, T., Kodadek, T. Inhibition of sequence-specific proteolysis using compounds thattarget the substrate rather than the enzyme. Chem.Biol., 2001,8, 391-397.
    4. Zhang, Z., Wang, L., Brock, A., Schultz, P. The Selective Incorporation of Alkenes into Proteins inEscherichia coli, Angew. Chem. Intl., 2002, 41, 2840- 2842.
    5. Wang, L., Zhang, Z., Brock, A., Schultz, P. Addition of the keto functional group to the genetic code of Escherichia coli, Proc. Natl. Acad. Sci. USA, 2003, 100,56- 61.
    6. Zhang, Z., Smith, B. A., Wang, L., Brock, A., Schultz, P. A new strategy for site- specific proteinmodification in vivo: genetic incorporation of keto amino acids into proteins. Biochemistry, 2003,42, 6735-6746.
    7. Chin, J. W., Cropp, T. A., Anderson, J. C., Mukhergi, M., Zhang, Z., Schultz, P. An expandedeukaryotic genetic code. Science, 2003, 301, 964-967.
    8. Alfonta, L., Zhang, Z., Uryu, S., Schultz, P.G. Site-specific incorporation ofredox dihydroxy-phenylalanine (DHP) into proteins. J. Am. Chem. Soc. 2003,125, 14662-14663.
    9. Zhang, Z., Alfonta, L., Feng, T., Uryu, S., Schultz, P.G. Selective incorporation of 5-hydroxy-tryptophan into proteins in mammalian cells. Proc.Natl. Acad. Soc. USA,2004,101, 8882-8887.
    10. Lu, C., Zhu, J., Wang. Y., Umeda, A., Lai, E., Comeadow, R., Moreno, G., Person, M., Zhang, Z.Staphylococcus aureus sortase A exists as a dimeric protein in vitro. Biochemistry, 2007, 46, 9346-9354.
    11. Zhu, J., Lu, C., Standland, M., Lai, E., Moreno, G., Umeda, A., Jia, X., Zhang, Z. Single mutation on the surface of Staphylococcus aureus sortase A can disrupt its dimerization. Biochemistry, 2008,47,1667-1674.
    12. Thibodeaux, G.N., Cowmeadow, R., Umeda, A., Zhang, Z. A tetracycline repressor-basedmammalian two-hybrid system to detect protein-protein interactions in vivo. Anal. Biochem. 2009,368,129-131.
    13. Umeda, A., Thibodeaux, G.N., Zhu, J., Lee, Y., Zhang, Z. Site-specific protein crosslinking with genetically incorporated 3,4-dihydroxy-L-phenylalanine. ChemBioChem, 2009, 10, 1302-1304.
    14. Umeda, A., Hou, T., Thibodeaux, G.N., Moncivais, K., Jiang, F., Zhang, Z. A Versatile Approach to Transform Low-Affinity Peptides into Protein Probes with Co-Translationally Expressed Chemical Cross-Linker, Analytical Biochemistry, 2010, 405(1):82-8. (Cover of the journal)
    15. Thibodeaux, G.N., Cowmeadow, R., Xiang, L., Alfonta, L., Zhang, Z. Transforming Methanococcusjannaschii amber suppressor tRNA : tyrosyl tRNA synthetase orthogonal pair evolved in Escherichia coli for its efficient function in mammalian cells. PlosOne, 2010, Vol. 5, issue 6, e11263.
    16. Umeda, A., Pranav, S., Wan, D., Chen, S., Zhang, Z., Femtosecond laser-- assisted optoporation for drug and gene delivery into single mammalian cells. J. Biomed. Nanotech., accepted, 2011, 7, 334-341.
    17. Xiang L, Moncivais K, Jiang F, Willams B, Alfonta, L, Zhang, Z.*, Crucial optimization of translational components towards efficient incorporation of unnatural amino acids into proteins in mammalian cells. PLoS One. 2013 Jul 12;8(7):e67333.
    18. Smolskaya S, Zhang Z.*, Alfonta L., Enhanced yield of recombinant proteins with site-specifically incorporated unnatural amino acids using a cell-free expression system. PLoS One. 2013 Jul 2;8(7):e68363.
    19. Zhang, Z.*, Equilibrium of sortase A dimerization on Staphylococcus aureus cell surface mediates its cell wall sorting activity-Implication towards the development of new antiinfective agents. Proceedings of Drug Discovery & Therapy World Congress, 2013, June.
    20. Moncivais, K., Zhang, Z.* Tetracycline Repressor-Based Mammalian Two- Hybrid Systems , in Two Hybrid Technologies: Methods in Molecular Biology, Eds. B. Sulter and E.E. Wanker, Human Press, January 5, 2012.
    21. Williams, B., Zhang, Z.* Reverse Protein Engineering Towards a Fluorescent Peptide, Protein Science, Vol. 23 Suppl 1, July 2014, p160.
    22. Zhu, J., Williams, B., Zhang, Z* Sortase A as a Tool Box for Protein and Cellular Engineering, Research in Microbiology, 2015, in revision.
    23. Zhu, J., Xiang, L., Jiang, F., Williams, B, Barata, J., Zhang, Z.* Equilibrium of sortaseA dimerization on Staphylococcus aureus cell surface mediates its cell wall sorting activity, J. Experimental Biology and Medicine, accepted for publication.
    24. Williams, B., Umeda, A., Chanthery, Y., Shimomura, E., Barata, J., Zhang, Z.* Molecular devolution: the development of a genetically encoded fluorescent peptide, Nature Biotechnology, submitted