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Department ofChemistry and Biochemistry

Brian McNelis

Brian J. McNelis

Associate Professor

Degree Information:

B.A., Gettysburg College, 1984
Ph.D., Duke University, 1990


Development and synthesis of novel azapeptoids as HIV Protease Inhibitors. Enantioselective amination of enolates and alkenes utilizing a chiral amination reagent. Atom-economy approach to enantiomer resolution utilizing the Mitsunobu reaction. Synthesis of nonlinear optic chromophores.

  • Organic Chemistry I, II, III (Chem 31, 31, 33)
  • Organic Synthesis (Chem 130)
  1. Emilee L. Sena*, Justin H. Peel*, Devin Wesenberg*, Shreya Nathan**, Marianne Wallis*, Maxwell J. Giammona*, Thorsteinn Adalsteinsson, Brian J. McNelis, and Richard P. Barber, Jr., “Transport and spectroscopic studies of the effects of Fullerene structure on the efficiency and lifetime of polythiophene-based solar cells,” Solar Energy Materials & Solar Cells,2012, 100, 192–198.
  2. B. J. McNelis, D. D. Sternbach, A. T. MacPhail, "Synthetic and kinetic studies of substituent effects in the furan intramolecular Diels-Alder reaction", Tetrahedron 50, 6767-82 (1994).
  3. J. T. Starr, G. S. Rai, H. Dang, B. J. McNelis, "An improved oxidation method for the synthesis of azodicarbonyl compounds",Synthetic Communications 27, 3197-3200 (1997).
  4. B. J. McNelis, "Mechanism templates: lecture aids for effective presentation of mechanism in introductory organic chemistry",Journal of Chemical Education 75, 479-481 (1998).
  5. B. J. McNelis, J. T. Starr, H. Dang, "Steric promotion of cyclization reactions: substituent effect studies in the furan intramolecular Diels-Alder reaction", Journal of Heterocyclic Chemistry 35, 1509-1513 (1998).
  6. B.J. McNelis, L.C. Nathan, and C.J. Clark, "Design, synthesis and crystal structure of a copper dimetallocyclophane complex exhibiting unique rotational isomerism", J. Chem. Soc. Dalton Trans., 1831-1834 (1999).
  7. A. Shachter, B. McNelis, and T. Shanks, "Integrating Ethics in Science into a Summer Undergraduate Research Program", New England Association of Chemistry Teachers Journal 18, 4 (1999).
  8. Tro, M; Sarabia, A; Bandaccari, KJ*; Oparko, D; Giammona, MJ; Isaac, J; Tajalli, P; Chesmore, GE*; Adalsteinsson, T; Barber, RP; McNelis; BJ “Structure Function Relationships of Fullerene Esters in Polymer Solar Cells: Unexpected Structural Effects on Lifetime and Efficiency” International Journal of Energy Research 2016, 40, 507.