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Lu, Bill


Dr. Lu obtained his MD in medicine and Ph.D. in Biochemistry and Human Genetics. His research interests center on finding innovative solutions to the most difficult to treat human diseases using genetic tools. He works with premed students to achieve their career goals.

  • MD. Shanghai Medical University, Clinical Medicine
  • Ph.D. University of Manitoba, Biochemistry and Medical Genetics
  • BS. University of Manitoba, Computer Sciences
Honors & Awards:
  • Technology Innovation Award, System Bioscience LLC, USA
  • Distinguished Ph.D. Dissertation Award, University of Manitoba, Canada
  • National Research Award, Susan G. Komen Breast Cancer Foundation, USA
  • Outstanding Research and Education Award, Fudan University, China
  • Young Investigator Award, Chinese Association of Pathophysiology, China
Courses Taught:
  • Undergraduate: Molecular and Cell Biology (BIOE22); Physiology and Anatomy for Engineers (BIOE171); Senior Design Project (BIOE194/195/196)
  • Graduate: Genome Engineering and Bioinformatics (BIOE263); Protein Engineering and Therapeutics (BIOE301); Gene and Cell Therapy (BIOE302); Master’s Thesis Research (BIOE397)
Academic Achievements:
  • Published over 50 research articles and book chapters
  • Filed 2 patents
  • Editorial board members
  • Ad hoc reviewers
Research Expertise:
  • Nano-vesicle for drug delivery: Development of cell-derived nano-vesicle for applications such as vesicle trafficking and imaging, drug delivery, targeted therapy. Pioneer in vesicle engineering for drug loading and tissue targeting. An inventor in genetic modification of nano-vesicle for the treatment of human diseases, including cancer, cardiovascular and neuronal disorders.
  • Genome engineering and gene therapy: Developed genome editing tools (TALEN, Cas-9, Cre-LoxP, and homologous recombinant vectors) for manipulating DNA sequences in living human cells. These technological tools are distributed world wide.
  • Molecular sensor and high throughput applications: Development of novel and advanced genetic systems such as a molecular circuit for signaling sensing, drug screening, and environmental and toxicity studies.
  • Molecular imaging and vesicular trafficking: Development of genetically encoded reporters for live-cell imaging and vesicular trafficking in human cells using an advanced confocal microscope and fluorescence-activated cell sorter.
Career Highlights:
  • Cancer researcher at UCSF
  • Medical intern in New York
  • Senior scientist, R&D Biotechnology in Bay Area 
  • Bioengineering undergraduate Grace Ling and Assistant Professor Bill Lu, M.D., Ph.D., are testing a new method of gene therapy that safely delivers DNA to mutated cells without using viruses for transport, as is the current norm.

    Bill Lu

    Associate Professor, 
    Department of Bioengineering